Syntara Ltd
Syntara Limited is an Australia-based clinical-stage drug development company.
The business
Syntara Limited is an Australia-based clinical-stage drug development company. The Company is targeting extracellular matrix dysfunction with its amine oxidase chemistry and other technologies to develop novel medicines for blood cancers and conditions linked to inflammation and fibrosis. The Company’s lead candidate SNT-5505 is for the bone marrow cancer myelofibrosis which causes a build-up of scar tissue that leads to loss of red and white blood cells and platelets. The Company is also advancing topical pan-LOX inhibitors in scar revision, keloid scarring and scar prevention post-surgery. Its product candidate, SNT-4728, is an inhibitor to treat sleep disorders and slow progression of neurodegenerative diseases like Parkinson’s by reducing neuroinflammation. The Company’s other drug candidates target fibrotic and inflammatory diseases such as kidney fibrosis, NASH, pulmonary fibrosis and cardiac fibrosis.
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Latest news

Syntara Expands Safety and Tolerability Study of SNT-9465 Topical Scar Treatment
Syntara expands Phase 1b trial for SNT-9465, adding 10 participants, new blinded design and Sydney site; top-line data due Q1 2027 to back an IND.

Syntara advances myelofibrosis trial with Phase 2 data and SNT-5505 FDA fast track designation
Clinical-stage drug developer Syntara (ASX: SNT) has hit more milestones with its SNT-5505 blood cancer treatment candidate. The company informed shareholders that it has obtained further positive interim data from its ongoing Phase 2 clinical trial evaluating SNT-5505 in combination with ruxolitinib (RUX) for the treatment of myelofibrosis. Myelofibrosis is a type of blood cancer […]
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