Nyrada Inc
Nyrada Inc. is an Australia-based biotechnology company. The Company is focused on the discovery and development of small-molecule therapies, specifically targeting Transient Receptor Potential Canonical (TRPC) ion channels. The Company’…
The business
Nyrada Inc. is an Australia-based biotechnology company. The Company is focused on the discovery and development of small-molecule therapies, specifically targeting Transient Receptor Potential Canonical (TRPC) ion channels. The Company’s lead candidate, Xolatryp, is a small molecule cardio protection and neuroprotection therapy. Xolatryp has demonstrated preclinical efficacy as an acute treatment following ischemic stroke, traumatic brain injury (TBI), and acute myocardial infarction (AMI). Xolatryp, is also a novel blocker targeting TRPC 3/6/7 ion channels, developed to mitigate secondary brain injury and prevent further brain cell death. The critical role of TRPC 3/6/7 channels in secondary injury has been validated in animal knockout models and through research-grade blockers. Its medical programs include Myocardial Ischemia and Arrhythmia Control, Stroke, and Traumatic Brain Injury.
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Latest news
Nyrada Raises Fresh Capital to Fund Xolatryp Phase IIa And Pipeline Expansion
Nyrada raises A$12m via placement to fund Xolatryp Phase IIa PROTECT-MI and pipeline expansion; targets a further A$2m via SPP, with board participation.
Nyrada Announces Preclinical Oncology Efficacy for Xolatryp and US Patent Allowance
Nyrada reports strong preclinical Xolatryp efficacy in liver cancer and a US patent allowance, highlighting a ~39% boost vs doxorubicin alone.
Nyrada Confirms Xolatryp Offers Mitochondrial Stabilisation after Traumatic Brain Injury
Nyrada (ASX: NYR) has confirmed its small molecule therapy Xolatryp can reduce mitochondrial calcium ion loading in the brain following traumatic injury. A collaborative study with the University of New South Wales and the Walter Reed Army Institute of Research sought to evaluate the efficacy of Xolatryp in a penetrating traumatic brain injury (TBI) rodent […]
Weekly wrap: rumours of wars send the ASX 200 tumbling
It is the Bible that talks about not being alarmed by “wars and rumours of wars” but Australian share market investors weren’t quite so sanguine, pushing down the ASX 200 sharply. By the close of trade on Friday 55.2 points or 0.7% had been erased from the ASX 200 as the reality of a worsening […]
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