Entropy Neurodynamics Ltd
Entropy Neurodynamics Limited, formerly Tryptamine Therapeutics Limited, is an Australia-based clinical-stage biotechnology company focused on developing proprietary, novel formulations for the administration of psilocin in combination w…
The business
Entropy Neurodynamics Limited, formerly Tryptamine Therapeutics Limited, is an Australia-based clinical-stage biotechnology company focused on developing proprietary, novel formulations for the administration of psilocin in combination with psychotherapy to treat diseases with unmet medical needs. The Company’s lead program, TRP-8803, is a proprietary formulation of IV infused psilocin (the active metabolite of psilocybin) with potential to alleviate numerous shortcomings of oral psilocybin including: significantly reducing the time to onset of the psychedelic state, controlling the depth and duration of the psychedelic experience, and reducing the overall duration of the intervention to a commercially feasible timeframe. The Company has completed a Phase 2a clinical trial for the treatment of binge eating disorder and for the treatment of fibromyalgia. Each of the studies is utilizing TRP-8802 (synthetic, oral psilocybin) to demonstrate clinical benefit in these indications.
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Latest news

Entropy Neurodynamics Appoints BioCina for Global Manufacture of TRP-8803 IV Psilocin
Entropy Neurodynamics appoints BioCina for global manufacture of TRP-8803 IV psilocin, enabling regulatory submissions and rapid scale-up across indications.

Entropy Neurodynamics Gains Ethics Approval for Eight-Indication TRP-8803 Trial
Entropy Neurodynamics gains ethics approval for Phase 1b/2a eight-indication TRP-8803 basket trial; first dosing this quarter.

Entropy Neurodynamics Reports Breakthrough Results from Phase 2a TRP-8802 Study for Treating IBS
Entropy Neurodynamics announces Phase 2a TRP-8802 IBS results: 75% responders, clear gut-brain axis effect; de-risks program ahead of TRP-8803 trials.

Entropy Neurodynamics' TRP-8803 Trial Shows Repeatable Psychedelic Effects in BED Study
Entropy Neurodynamics reports repeatable psychedelic effects in TRP-8803 BED trial; Cohort 2 enrollment advancing; R&D incentives boost cash runway.
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