Biotech

Memphasys pilot study confirms RoXsta’s potential as high-throughput antioxidant diagnostic tool

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By Imelda Cotton - 
Memphasys ASX MEM Successful trial RoXsta Mega Cell High-Throughput
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A pilot study has shown that Memphasys’ (ASX: MEM) RoXsta Mega Cell high-throughput assay device can conduct large-scale, simultaneous antioxidant assays within a lab setting.

The study demonstrated that the next-generation analytical platform was able to process 96 samples in less than one hour, returning highly accurate antioxidant readings for individuals requiring antioxidant therapy.

The findings expand the commercial opportunities for RoXsta technology in targeted fields where its capacity for rapid, reliable antioxidant measurement has the potential to make a meaningful impact.

Continued momentum

Memphasys managing director Dr David Ali said the pilot study results provided solid momentum for RoXsta’s continued development.

“To date, much of our focus has been on smaller-scale assessments of RoXsta, ensuring the results are accurate and the device is capable of being deployed in a commercial setting,” he said.

“The success of this pilot study suggests we can move into the next development phase, where we will identify significant opportunities and optimise antioxidant testing for commercial and research-led laboratories.”

High-capacity testing

RoXsta performs rapid, high-capacity testing for reactive oxygen species (ROS) levels in biological samples by detecting imbalances between free radicals and antioxidants.

Oxidative stress occurs when there is an imbalance between harmful ROS and the body’s antioxidant defences.

When elevated, this stress can cause cellular damage associated with conditions including infertility, degenerative diseases and impaired physical performance.

Strong correlation

Memphasys has uncovered a strong correlation in human health between the oxidative stress measurements captured by RoXsta and sperm functionality, highlighting the system’s potential for diagnosing male infertility.

The company is currently analysing the preliminary findings from a similar study in the thoroughbred horse racing industry investigating how physical exertion and oxidative stress can affect reproductive health.

Research comparing RoXsta to other antioxidant systems has highlighted its versatility and ability to deliver results in a shorter timeframe and at a fraction of the cost, making it a powerful diagnostic tool for rapid, point-of-care assessments.